Article
Integrated transcriptomics of multiple sclerosis peripheral blood mononuclear cells identified COPG1, RPN1, and KDM3B as potential biomarkers
2024-08-09
Abstract excerpt
<title>Abstract</title> <p>Among diagnostic techniques, RNA biomarkers have been poorly investigated for multiple sclerosis (MS). In this study, by the integration of GSE21942 and GSE203241 microarray profiles of peripheral blood mononuclear cells, potential biomarkers were explored. A comparison between 28 MS patients and 23 healthy controls led to the identification of 71 upregulated and 35 downregulated genes....
Topics
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- Bioinformatics and Genomic Networks
- Cancer-related molecular mechanisms research
- Cytokine Signaling Pathways and Interactions
- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- Multiple Sclerosis Research Studies
- Rheumatoid Arthritis Research and Therapies
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 959bef42-e78f-5ecc-b857-9e10bea6fd81
- DOI
- 10.21203/rs.3.rs-4685812/v1
