Article

Integrated multi-omics profiling uncovers the epigenetic, transcriptional, and metabolic landscape of prostate cancer progression

2026-02-13

Abstract excerpt

A comprehensive understanding of the underlying molecular mechanisms of prostate cancer is essential for the development of precise diagnostic biomarkers. In this study, we applied unsupervised multi-omics factor analysis (MOFA) to integrate DNA methylation, gene expression, and metabolic profiles derived from the same individuals, aiming to characterize the biological landscape of normal, malignant, and aggressiv...

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Literature Corpus work: 08a2035e-e8cb-5f3d-899d-53b397ca3f76
DOI: 10.64898/2026.02.11.704810

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