Article

Low frequency ultrasound enhances chemotherapy sensitivity and induces autophagy in human paclitaxel resistance prostate cancer PC-3R cells through the ERs-mediated PI3K/Akt/mTOR signaling pathway

2018-05-21

Abstract excerpt

Sonodynamic therapy (SDT) as an emerging tumor-assisting method has attracted a great deal of interest in tumor therapy research in recent years. However, autophagy has been observed in several cancer cells treated with SDT and its role and mechanism are not clear. In the present study, we have investigated the effect of low frequency ultrasound on paclitaxel(PTX) resistance prostate cancer PC-3R cells and demonst...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 088a8ff5-89b6-54a1-bd14-75a85b980227
DOI: 10.1101/326629

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Low frequency ultrasound enhances chemotherapy sensitivity and induces autophagy in human paclitaxel resistance prostate cancer PC-3R cells through the ERs-mediated PI3K/Akt/mTOR signaling pathwayDOI 10.1101/326629Read

Low Intensity Ultrasound Promotes the Sensitivity of Rat Brain Glioma to Doxorubicin by Down-Regulating the Expressions of P-Glucoprotein and Multidrug Resistance Protein 1 In Vitro and In VivoSemantic proximity Read

Olaparib reverses prostate cancer resistance to Rapamycin by promoting macrophage polarization towards the M1 phenotypeSemantic proximity Read

TP53 Genotype-Dependent Cellular Responses to DVDMS-Sonodynamic Therapy in Oral Squamous Cell Carcinoma.Semantic proximity Read

Long non‐coding RNA PRRT3‐AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagySemantic proximity Read

Aerobic physical exercise enhances nanoparticle efficacy in prostate cancer treatmentSemantic proximity Read

Oxidative Stress Resistance in Metastatic Prostate Cancer: Renewal by Self-EatingSemantic proximity Read

Organic anion transporters and PI3K–AKT–mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rheinSemantic proximity Read

Synergistic effects of negative-charged nanoparticles assisted by ultrasound on the reversal multidrug resistance phenotype in breast cancer cells.Semantic proximity Read

Ultrasound–guided percutaneous laser ablation for pancreatic cancer: a new treatment optionSemantic proximity Read

Three Birds with One Stone: Co-Encapsulation of Diclofenac and DL-Menthol for Realizing Enhanced Energy Deposition, Glycolysis Inhibition and Anti-Inflammation in HIFU SurgerySemantic proximity Read

A Sonosensitizer-based Polymeric Nanoplatform for Realizing Chemo-sonodynamic Combination Therapy of Lung Cancer Semantic proximity Read

Acquisition of epithelial-mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance.Semantic proximity Read