Article
Acquisition of epithelial-mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance.
Cell death & disease - 24 Oct 2013
Chang L, Graham P H, Hao J, Ni J, Bucci J, Cozzi P J, Kearsley J H, Li Y
Abstract excerpt
Radioresistance is a major challenge in prostate cancer (CaP) radiotherapy (RT). In this study, we investigated the role and association of epithelial-mesenchymal transition (EMT), cancer stem cells (CSCs) and the PI3K/Akt/mTOR signaling pathway in CaP radioresistance. We developed three novel Ca...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.