Article
Implications of venous thromboembolism GWAS reported genetic makeup in the clinical outcome of ovarian cancer patients.
The pharmacogenomics journal - 1 Apr 2021
Tavares Valéria, Pinto Ricardo, Assis Joana, Coelho Sara, Brandão Mariana, Alves Sara, Pereira Deolinda, Medeiros Rui
Abstract excerpt
Ovarian cancer (OC) represents the most lethal gynaecological neoplasia. Conversely, venous thromboembolism (VTE) and OC are intricately connected, with many haemostatic components favouring OC progression. In light of this bilateral relationship, genome-wide association studies (GWAS) have reported several single-nucleotide polymorphisms (SNPs) associated with VTE risk that could be used as predictors of OC...
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