Back to search

Article

A DNA Vaccine Inducing T Cell Responses Against CCHF: From in silico to in vivo

2025-05-22

Abstract excerpt

<title>Abstract</title> <p><bold>Objectives</bold> Crimean-Congo Hemorrhagic Fever is a severe viral disease with high fatality rates, and no approved vaccine is currently available. This study aimed to design and evaluate a multi-epitope recombinant vaccine for Crimean-Congo Hemorrhagic Fever using computational and in vitro approaches. The data presented in this study were generated to assess the immunogenic po...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0828007a-621c-5680-8920-287bead6c2f5
DOI
10.21203/rs.3.rs-6238452/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A DNA Vaccine Inducing T Cell Responses Against CCHF: From in silico to in vivoDOI 10.21203/rs.3.rs-6238452/v1
In silico design and analyses of a multi-epitope vaccine against Crimean-Congo hemorrhagic fever virus through reverse vaccinology and immunoinformatics approachesSemantic proximity
An Immunoinformatics Approach to Design a Potent Multi-Epitope Vaccine against Asia-1 Genotype of Crimean–Congo Haemorrhagic Fever Virus Using the Structural Glycoproteins as a TargetSemantic proximity
Discovery of potential immune epitopes and peptide vaccine design - a prophylactic strategy against Rift Valley fever virusSemantic proximity
Adjuvant Potential of CD24 on Immunogenicity and Lethal Challenge Protection of a DNA vector Expressing Nucleocapsid Protein of Crimean Congo Hemorrhagic Fever VirusSemantic proximity
Immunoinformatics-Driven Design and In Silico Validation of a Multi Epitope Subunit Vaccine Targeting NorovirusSemantic proximity
Design and In Silico Validation of a Novel Multi-Epitopes Subunit Vaccine Candidate against Lassa Virus Using Reverse Vaccinology ApproachSemantic proximity
A pan-genomic analysis based multi-epitope vaccine development by targeting Stenotrophomonas maltophilia using reverse vaccinology method: An in-silico approachSemantic proximity
Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged MiceSemantic proximity
Reverse vaccinology-based design of a universal multiepitope vaccine against chikungunya virus: phylogenetic and immunoinformatics approachesSemantic proximity
Potential Immunogenic Activity of Computationally Designed mRNA- and Peptide-Based Prophylactic Vaccines against MERS, SARS-CoV, and SARS-CoV-2: A Reverse Vaccinology ApproachSemantic proximity
Immunological Analysis of a CCHFV mRNA Vaccine Candidate in Mouse ModelsSemantic proximity
Design of multivalent-epitope vaccine models directed toward the world’s population against HIV-Gag polyprotein: Reverse vaccinology and immunoinformaticsSemantic proximity
Select a neighboring publication to make it the new centre.