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Article

Immunological Analysis of a CCHFV mRNA Vaccine Candidate in Mouse Models

16 Sept 2019

Abstract excerpt

Development of new vaccine platforms against viral diseases is considered urgent. In recent years, mRNA constructs have attracted great interest in this field due to unique advantages over conventional gene transfer platforms. In the present study, we developed a new naked conventional mRNA vaccine expressing the non-optimized small (S) segment of the Ank-2 strain of Crimean-Congo Hemorrhagic Fever virus (CCHFV)....

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PMID: 31527460
DOI: 10.3390/vaccines7030115

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