Article

Patient-specific cell communication networks associate with disease progression in cancer

2021-02-10

Abstract excerpt

The maintenance and function of tissues in health and disease depends on cell-cell communication. This work shows how high-level features, representing cell-cell communication, can be defined and used to associate certain signaling ‘axes’ with clinical outcomes. Using cell-sorted gene expression data, we generated a scaffold of cell-cell interactions and define a probabilistic method for creating per-patient weigh...

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Literature Corpus work: 081dee9d-df1d-57ad-8d6f-49f647e2cc2a
DOI: 10.1101/2021.02.08.430343

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