Article

Patient DNA cross-reactivity of the CDC SARS-CoV-2 extraction control leads to an inherent potential for false negative results

2020-05-14

Abstract excerpt

Testing for RNA viruses such as SARS-CoV-2 requires careful handling of inherently labile RNA during sample collection, clinical processing, and molecular analysis. Tests must include fail-safe controls that affirmatively report the presence of intact RNA and demonstrate success of all steps of the assay. A result of “no virus signal” is insufficient for clinical interpretation: controls must also say “The reactio...

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Literature Corpus work: 0804589c-addd-50f4-8699-81d122b78092
DOI: 10.1101/2020.05.13.094839

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Patient DNA cross-reactivity of the CDC SARS-CoV-2 extraction control leads to an inherent potential for false negative resultsDOI 10.1101/2020.05.13.094839Read

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