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Cautionary Note on Contamination of Reagents Used for Molecular Detection of SARS-CoV-2

4 Sept 2020

Abstract excerpt

Reverse transcription (RT)-PCR, the principal diagnostic method applied in the worldwide struggle against COVID-19, is capable of detecting a single molecule of a viral genome. Correctly designed and practiced RT-PCR assays for SARS-CoV-2 should not cross-react with similar but distinct viral pathogens, such as the coronaviruses associated with the common cold, and should perform with very high analytical...

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PMID: 32894756
DOI: 10.1093/clinchem/hvaa214

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