Article

Overhauling a faulty control in the CDC-recommended SARS-CoV-2 RT-PCR test panel

2020-06-13

Abstract excerpt

<h4>ABSTRACT</h4> To battle the COVID-19 pandemic, widespread testing for the presence of the SARS-CoV-2 virus is worldwide being employed by specific real-time RT-PCR (rRT-PCR) of viral RNA. The CDC has issued a recommended panel of PCR-based test sets that entail several primer/probe sets that target the SARS-CoV-2 N-gene, but also one that targets the human RNase P gene (h-RP) as a positive control for RNA ext...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 03efcb99-0fb2-5a35-8eed-04a0ea0a1849
DOI: 10.1101/2020.06.12.147819

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Overhauling a faulty control in the CDC-recommended SARS-CoV-2 RT-PCR test panelDOI 10.1101/2020.06.12.147819Read

Patient DNA cross-reactivity of the CDC SARS-CoV-2 extraction control leads to an inherent potential for false negative resultsSemantic proximity Read

RT-qPCR Diagnostics: The “Drosten” Sars-Cov-2 Assay ParadigmSemantic proximity Read

How to choose the right real-time RT-PCR primer sets for the SARS-CoV-2 genome detection? Semantic proximity Read

RNA Extraction Alternative Method for SARS-CoV-2 Molecular DiagnosisSemantic proximity Read

ASSESSMENT OF POTENTIAL SARS-CoV-2 VIRUS N GENE INTEGRATION INTO HUMAN GENOME REVEALS NO SIGNIFICANT IMPACT ON RT-qPCR COVID-19 DIAGNOSTIC TESTINGSemantic proximity Read

How to choose the right real-time RT-PCR primer sets for the SARS-CoV-2 genome detection?Semantic proximity Read

RT-PCR based SARS-CoV-2 variant screening assays require careful quality controlSemantic proximity Read

Identification of mutations in SARS-CoV-2 PCR primer regionsSemantic proximity Read

COVID-19 PCR: frequency of internal control inhibition in the clinical practiceSemantic proximity Read

Insufficient Sensitivity of RNA Dependent RNA Polymerase Gene of SARS-CoV-2 Viral Genome as Confirmatory Test using Korean COVID-19 CasesSemantic proximity Read

Genomic Variations in SARS-CoV-2 Strains at the Target Sequences of Nucleic Acid Amplification TestsSemantic proximity Read

Multiplex real-time RT-PCR method for the diagnosis of SARS-CoV-2 by targeting viral N2, RdRP and human RP genesSemantic proximity Read