Article

Self-iterative multiple instance learning enables the prediction of CD4 <sup>+</sup> T cell immunogenic epitopes

2025-02-04

Abstract excerpt

Accurately predicting the antigen presentation to CD4 + T cells and subsequent induction of immune response is fundamentally important for vaccine development, autoimmune disease treatments, and cancer neoepitope identification. In immunopeptidomics, single-allelic data are highly specific but limited in allele scope, while multi-allelic data contain broader coverage at the cost of weakly labeling. Existing compu...

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Literature Corpus work: 07e2a6d6-4fc4-511d-b933-b02f21f93bb1
DOI: 10.1101/2025.02.02.636141

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