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Disease-specific loss of microbial cross-feeding interactions in the human gut

20 Oct 2023

Abstract excerpt

Many gut microorganisms critical to human health rely on nutrients produced by each other for survival; however, these cross-feeding interactions are still challenging to quantify and remain poorly characterized. Here, we introduce a Metabolite Exchange Score (MES) to quantify those interactions. Using metabolic models of prokaryotic metagenome-assembled genomes from over 1600 individuals, MES allows us to...

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PMID: 37863966
DOI: 10.1038/s41467-023-42112-w

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