Article

SegJointGene: joint cell segmentation and spatial gene prioritization by information entropy guided convolutional neural networks

2026-01-09

Abstract excerpt

<h4>Motivation</h4> Spatial sequencing technologies enable the single-cell-level study of molecular organization in tissues. Revealing such spatial patterns relies on accurate cell segmentation. In complex tissues with dense cell packing, segmentation based solely on nuclear staining is insufficient for accurate cell boundary detection. This limitation arises because accurate segmentation necessitates the delinea...

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Literature Corpus work: 0670c546-0224-5cf4-95e0-3a4b06460736
DOI: 10.64898/2026.01.08.698474

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