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Parallel profiling of antigenicity alteration and immune escape of SARS-CoV-2 Omicron and other variants

8 Feb 2022

Abstract excerpt

SARS-CoV-2 variants have evolved a variety of critical mutations, leading to antigenicity changes and immune escape. The recent emerging SARS-CoV-2 Omicron variant attracted global attention due to its significant resistance to current antibody therapies and vaccines. Here, we profiled the mutations of Omicron and other various circulating SARS-CoV-2 variants in parallel by computational interface analysis and in...

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PMID: 35136040
DOI: 10.1038/s41392-022-00910-6

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