Article

KIF23 regulation by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma

2023-11-20

Abstract excerpt

<h4>Background & Aims</h4> In hepatocellular carcinoma, there is a lack of successful translation of experimental targets identified in mouse models to human patients. In this study, we used a comprehensive transcriptomic approach in mice to identify novel potential targets for therapeutic intervention in humans. <h4>Methods</h4> We analysed combined genome-wide miRNA and mRNA expression data in three pathogenic...

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Literature Corpus work: 061d0326-ef71-5530-b61f-d63142d260f8
DOI: 10.1101/2023.11.20.565448

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