Article

A recall-by-genotype study on polymorphisms in the TMPRSS6 gene and oral iron absorption: a study protocol

2021-01-04

Abstract excerpt

<h4>Background: </h4> : Oral iron supplementation is commonly used to treat and prevent anaemia. The transmembrane protease serine 6 gene ( TMPRSS6 ) , which encodes matriptase 2, is a negative regulator of hepcidin, the key controller of iron homeostasis. Genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) in the TMPRSS6 gene that are associated with an increas...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0570796b-ede7-54f0-858e-215304fd6e2a
DOI: 10.12688/f1000research.19080.2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A recall-by-genotype study on polymorphisms in the TMPRSS6 gene and oral iron absorption: a study protocolDOI 10.12688/f1000research.19080.2Read

The impact of single nucleotide polymorphisms in human genes that regulate hepcidin and iron on oral iron absorption and the risk of anaemia in AfricansSemantic proximity Read

Association of common TMPRSS6 and TF gene variants with hepcidin and iron status in healthy rural Gambians.Semantic proximity Read

Association of the Transmembrane Protease Serine 6 rs855791 Variant and Nongenetic Factors With Iron Deficiency Among Female Medical Students in Yogyakarta: Protocol for a Case-Control Study.Semantic proximity Read

The role of TMPRSS6 gene polymorphism in iron resistance iron deficiency anaemia (IRIDA): a systematic review.Semantic proximity Read

TMPRSS6 gene polymorphisms associated with iron deficiency anaemia among global populationSemantic proximity Read

Impact of TMPRSS6 Genetic Variants on Maternal Iron Status in Pregnancy: A Systematic Review.Semantic proximity Read

TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia.Semantic proximity Read

TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individualsSemantic proximity Read

Functional and clinical impact of novel TMPRSS6 variants in iron-refractory iron-deficiency anemia patients and genotype-phenotype studies.Semantic proximity Read

Associations of genetically determined iron status across the phenome: A mendelian randomization studySemantic proximity Read

The association of TMPRSS6 gene polymorphism with iron status in Egyptian children (a pilot study).Semantic proximity Read

The global prevalence and ethnic heterogeneity of iron-refractory iron deficiency anaemiaSemantic proximity Read