Article

An <i>in silico</i> approach to determine inter-subunit affinities in human septin complexes

2022-12-20

Abstract excerpt

The septins are a conserved family of filament-forming guanine nucleotide binding proteins, often named the fourth component of the cytoskeleton. Correctly assembled septin structures are required for essential intracellular processes such as cytokinesis, vesicular transport, polarity establishment, and cellular adhesion. Structurally, septins belong to the P-Loop NTPases but they do not mediate signals to effecto...

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Literature Corpus work: d3adc290-9b4c-519a-8c37-229ff453182b
DOI: 10.1101/2022.12.20.521017

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