Article
Differential transcriptomic host responses in the early phase of viral and bacterial infections in human lung tissue explants ex vivo
2024-06-26
Abstract excerpt
<title>Abstract</title> <p>Background . The first 24 hours of infection represent a critical time window in interactions between pathogens and host tissue. However, it is not possible to study such early events in human lung during natural infection due to lack of clinical access to tissue this early in infection. We, therefore, applied RNA sequencing to <italic>ex vivo</italic> cultured human lung tissue explan...
Topics
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- Cancer-related molecular mechanisms research
- Cystic Fibrosis Research Advances
- Influenza Virus Research Studies
- Inhalation and Respiratory Drug Delivery
- interferon and immune responses
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mycobacterium research and diagnosis
- Respiratory viral infections research
Identifiers and source
- Literature Corpus work
- 053861e5-572d-549e-80b7-c064c36d84a9
- DOI
- 10.21203/rs.3.rs-4499225/v1
