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Proteolytic extraction enhances specific detection of the novel ‘S’-type low molecular weight glutenin subunit in wheat by monoclonal antibody

2012-01-01

Abstract excerpt

Specificity of monoclonal antibodies (MAbs) is required in diagnostic immunoassays. However, structural homology between a target antigen and other cellular proteins often causes promiscuous cross-reactivity of a MAb to proteins other than its target antigen, thereby hindering specificity. It is proposed in this study that specific proteolytic enzymes could be useful in the reduction or elimination of cross-reacti...

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Literature Corpus work
04d89f73-1e17-5ea4-9d77-a2bf084cbd11
DOI
10.1016/j.jcs.2011.08.015
Open publication

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Proteolytic extraction enhances specific detection of the novel ‘S’-type low molecular weight glutenin subunit in wheat by monoclonal antibodyDOI 10.1016/j.jcs.2011.08.015
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