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Design and evaluation of octopromycin-derived peptides as multifunctional antimicrobial agents against multidrug- resistant pathogens

2025-09-10

Abstract excerpt

<title>Abstract</title> <p> Octopromycin (OPM), an antimicrobial peptide from <italic>Octopus minor</italic> , shows potent activity against multidrug-resistant (MDR) <italic>Acinetobacter baumannii</italic> . Guided by the structure–activity relationship of the N-terminal domain OPM23, we designed short α-helical peptides with enhanced antimicrobial, anti-inflammatory, and antibiofilm properties while maint...

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Literature Corpus work
04d4f824-df78-5e15-9de6-748b8088c687
DOI
10.21203/rs.3.rs-7499194/v1
Open publication

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