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Article

Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer

2018-01-20

Abstract excerpt

<h4>ABSTRACT</h4> MiR-1 and miR-143 are frequently reduced in human prostate cancer (PCa), while miR-141 and miR-21 are frequently elevated. Consequently, these miRNAs have been studied as cell-autonomous tumor suppressors and oncogenes. However, the cell-type specificity of these miRNAs is not well defined in prostate tissue. Through two different microdissection techniques, and droplet digital RT-PCR, we quanti...

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Identifiers and source

Literature Corpus work
04339dc5-e3dd-5e80-94ca-97510d9c105e
DOI
10.1101/251090
Open publication

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Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancerDOI 10.1101/251090
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