Article
RORβ modulates a gene program that is protective against articular cartilage damage
2022-05-05
Abstract excerpt
Osteoarthritis (OA) is the most prevalent chronic joint disease which increases in frequency with age eventually impacting most people over the age of 65. OA is the leading cause of disability and impaired mobility, yet the pathogenesis of OA remains unclear. Treatments have focused mainly on pain relief and reducing joint swelling. Currently there are no effective treatments to slow the progression of the disease...
Topics
Open a Topic to create a Post that cites this publication.
- Arthritis, Experimental
- Bone Metabolism and Diseases
- Cytokine Signaling Pathways and Interactions
- Estrogen and related hormone effects
- Inflammatory mediators and NSAID effects
- Osteoarthritis Treatment and Mechanisms
- Tissue Engineering and Regenerative Medicine
- Wnt/β-catenin signaling in development and cancer
Identifiers and source
- Literature Corpus work
- 0427509f-d3fb-55aa-b048-db21ea5d10da
- DOI
- 10.1101/2022.05.05.490839
