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Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of <i>night owl/LZTR1</i> and <i>NF1</i> in GABAergic sleep control

2019-09-05

Abstract excerpt

The human 22q11.2 chromosomal deletion is one of the strongest identified genetic risk factors for schizophrenia. Although the deletion spans a number of genes, the contribution of each of these to the 22q11.2 deletion syndrome (DS) is not known. To investigate the effect of individual genes within this interval on the pathophysiology associated with the deletion, we analyzed their role in sleep, a behavior affect...

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Literature Corpus work
041c21a9-c675-5755-a8b6-068aa30574f0
DOI
10.1101/755454
Open publication

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Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of <i>night owl/LZTR1</i> and <i>NF1</i> in GABAergic sleep controlDOI 10.1101/755454
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