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Identification of CD4+ T cells with T follicular helper cell characteristics in the pig

3 Jun 2022

Abstract excerpt

T follicular helper (Tfh) cells provide help to germinal center B cells for affinity maturation , class switch and memory formation. Despite these important functions, this subset has not been studied in detail in pigs due to a lack of species-specific antibodies. We investigated putative Tfh cells from lymphoid tissues and blood of healthy pigs by using cross-reactive antibodies for inducible T-cell costimulator...

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PMID: 35667468
DOI: 10.1016/j.dci.2022.104462

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