Article

<i>SignalingProfiler</i> 2.0: a network-based approach to bridge multi-omics data to phenotypic hallmarks

2024-01-29

Abstract excerpt

Unraveling the cellular signaling remodeling upon a perturbation is a fundamental challenge to understand disease mechanisms and to identify potential drug targets. In this pursuit, computational tools that generate mechanistic hypotheses from multi-omics data have invaluable potential. Here we present SignalingProfiler 2.0, a multi-step pipeline to systematically derive context-specific signaling models by integ...

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Identifiers and source

Literature Corpus work: 0401e634-b212-529a-beec-a683ffcc6a4d
DOI: 10.1101/2024.01.25.577229

Open publication

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