Article

RatesTools: a Nextflow pipeline for detecting <i>de novo</i> germline mutations in pedigree sequence data

2022-07-20

Abstract excerpt

<h4>Summary</h4> Here, we introduce RatesTools , an automated pipeline to infer de novo mutation rates from parent-offspring trio data of diploid organisms. By providing a reference genome and high-coverage, whole-genome resequencing data of a minimum of three individuals (sire, dam, offspring), RatesTools provides a list of candidate de novo mutations and calculates a putative mutation rate. RatesTools uses s...

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Literature Corpus work: 03f45bb0-f585-568c-afff-447d94922c17
DOI: 10.1101/2022.07.18.500472

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