Article

Mutationathon: towards standardization in estimates of pedigree-based germline mutation rates

2021-08-31

Abstract excerpt

In the past decade, several studies have estimated the human per-generation germline mutation rate using large pedigrees. More recently, estimates for various non-human species have been published. However, methodological differences among studies in detecting germline mutations and estimating mutation rates make direct comparisons difficult. Here, we describe the many different steps involved in estimating pedigr...

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Literature Corpus work: 59dcd158-9cfc-5560-8ac6-05ea7fec5c65
DOI: 10.1101/2021.08.30.458162

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