Article

Single-nucleus ATAC-seq elucidates major modules of gene regulation in the development of non-alcoholic fatty liver disease

2022-09-01

Abstract excerpt

<title>Abstract</title> <p>Background Non-alcoholic fatty liver disease (NAFLD) develops from fatty liver to steatohepatitis during which multiple cell types may play different roles. Aiming to understand tissue composition of cell types, their gene expression and global gene regulation in the development of NAFLD, we performed single-nucleus and bulk ATAC-seq on the liver of rats fed with a high-fat diet (HFD)....

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Literature Corpus work: 03caa106-80d1-5237-b2b8-0e70ccc0bbd4
DOI: 10.21203/rs.3.rs-1907697/v1

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