Article

Functional investigation and two-sample Mendelian randomization study of non-alcoholic fatty liver disease hub genes obtained by WGCNA

2023-10-31

Abstract excerpt

<h4>Objective: </h4> Non-alcoholic fatty liver disease (NAFLD) poses significant health risks, including the potential progression to more severe liver conditions such as liver fibrosis, cirrhosis, and even hepatocellular carcinoma, but its underlying mechanisms are not well understood. This study aimed to identify potential hub genes for NAFLD and evaluate their clinical application in predicting the condition. <...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2041284a-56fb-5503-89c0-3f1a00601051
DOI: 10.21203/rs.3.rs-3504193/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Functional investigation and two-sample Mendelian randomization study of non-alcoholic fatty liver disease hub genes obtained by WGCNADOI 10.21203/rs.3.rs-3504193/v1Read

Identification of novel targets associated with cholesterol metabolism in nonalcoholic fatty liver disease: a comprehensive study using Mendelian randomization combined with transcriptome analysisSemantic proximity Read

Bioinformatics analysis of differentially expressed genes in non alcoholic fatty liver disease using next generation sequencing dataSemantic proximity Read

Identification of significant modules and hub genes involved in hepatic encephalopathy using WGCNASemantic proximity Read

Integrative analysis identifies oxidative stress biomarkers in non-alcoholic fatty liver disease via machine learning and weighted gene co-expression network analysisSemantic proximity Read

WGCNA‐Based Identification of Hub Genes and Key Pathways Involved in Nonalcoholic Fatty Liver DiseaseSemantic proximity Read

An novel effective and safe model for the diagnosis of nonalcoholic fatty liver disease in China: gene excavations, clinical validations, and mechanism elucidationSemantic proximity Read

Identification of Hub Genes Associated With Non-alcoholic Steatohepatitis Using Integrated Bioinformatics AnalysisSemantic proximity Read

Identification of a hub gene in hepatocellular carcinoma induced by nonalcoholic fatty liver disease using bioinformatics analysisSemantic proximity Read

Characterization of transcriptional modules related to fibrosing-NAFLD progressionSemantic proximity Read

Identification and validation of potential diagnostic signature and immune cell infiltration for NAFLD based on cuproptosis-related genes by bioinformatics analysis and machine learningSemantic proximity Read

Integrative network-based analysis on multiple Gene Expression Omnibus datasets identifies novel immune molecular markers implicated in non-alcoholic steatohepatitisSemantic proximity Read

Bioinformatics analysis explores potential hub genes in nonalcoholic fatty liver diseaseSemantic proximity Read