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A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease

5 Oct 2021

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease worldwide. We performed network analysis to investigate the dysregulated biological processes in the disease progression and revealed the molecular mechanism underlying NAFLD. Based on network analysis, we identified a highly conserved disease-associated gene module across three different NAFLD cohorts and highlighted the...

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Lipid metabolism and disorders
Liver Disease Diagnosis and Treatment
Peroxisome Proliferator-Activated Receptors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34712920
DOI: 10.1016/j.isci.2021.103222

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