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A Novel Standardized Propolis Extract Modulates Oxidative Stress-Induced Senescence in Human Dermal Fibroblasts by Suppressing SASP and Modulating Cell Cycle-Associated Gene Expression: A Preliminary In Vitro Investigation

2026-01-13

Abstract excerpt

<title>Abstract</title> <p> Background Cellular senescence, often driven by oxidative stress, is a fundamental driver of skin aging ("inflammaging"). While natural extracts are promising senomodulators, traditional propolis extracts suffer from inconsistent composition and problematic solvents. We have developed a novel, non-alcoholic solvent system based on Polyethylene Glycol (PEG) 400 and lecithin, which, th...

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Literature Corpus work: 03a41ac4-ce21-51a1-ae79-be0bc89bf16f
DOI: 10.21203/rs.3.rs-8572260/v1

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