Article

AKT1/mTOR/RICTOR risk variants in Indian hypertrophic cardiomyopathy patients

2026-07-27

Abstract excerpt

Hypertrophic cardiomyopathy is a hereditary heart muscle disease characterized by abnormal ventricular thickening and is predominantly caused by mutations in sarcomeric and signaling genes. Despite these advances, a substantial proportion of patients carry no identifiable pathogenic variants in these genes. Recently, we have shown that mutations in the RPS6KB1 gene (a member of the Akt signaling pathway) can lead...

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Literature Corpus work: 038085e0-f221-5d94-addc-394fc86f7efe
DOI: 10.64898/2026.07.23.26358782

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