Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical Presentation and Natural History of Hypertrophic Cardiomyopathy in RASopathies.

Heart failure clinics - 1 Apr 2018

Calcagni Giulio, Adorisio Rachele, Martinelli Simone, Grutter Giorgia, Baban Anwar, Versacci Paolo, Digilio Maria Cristina, Drago Fabrizio, Gelb Bruce D, Tartaglia Marco, Marino Bruno

Abstract excerpt

RASopathies are a heterogeneous group of genetic syndromes characterized by mutations in genes that regulate cellular processes, including proliferation, differentiation, survival, migration, and metabolism. Excluding congenital heart defects, hypertrophic cardiomyopathy is the most frequent cardiovascular defect in patients affected by RASopathies. A worse outcome (in terms of surgical risk and/or mortality) has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy, Hypertrophic
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Mutation

Share to ras Proteins

Source

Identifiers

PMID: 29525650
DOI: 10.1016/j.hfc.2017.12.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical Presentation and Natural History of Hypertrophic Cardiomyopathy in RASopathies.PMID 29525650Read ↗

The heart in RASopathies.Semantic proximity Read ↗

RASopathies in Cardiac DiseaseSemantic proximity Read ↗

RASopathies and Cardiac Complications: Insights into Mechanisms, Diagnosis, and Innovative Treatments.Semantic proximity Read ↗

Cardiac defects, morbidity and mortality in patients affected by RASopathies. CARNET study results.Semantic proximity Read ↗

Cardiovascular Characteristics and Progressions of Hypertrophic Cardiomyopathy and Pulmonary Stenosis in RASopathy Syndrome in the Genomic Era.Semantic proximity Read ↗

Natural history of hypertrophic cardiomyopathy.Semantic proximity Read ↗

Cardiac Phenotype and Gene Mutations in RASopathies.Semantic proximity Read ↗

Current management of hypertrophic cardiomyopathy.Semantic proximity Read ↗

Clinical and mutation profile of pediatric patients with RASopathy-associated hypertrophic cardiomyopathy: results from a Chinese cohortSemantic proximity Read ↗

RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it.Semantic proximity Read ↗

Genotype-cardiac phenotype correlations in a large single-center cohort of patients affected by RASopathies: Clinical implications and literature review.Semantic proximity Read ↗

RASopathies and cardiac manifestationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.