Article
Heritability Analysis of Life Span in a Semi-isolated Population Followed Across Four Centuries Reveals the Presence of Pleiotropy Between Life Span and Reproduction
24 Sept 2010
Abstract excerpt
Although genetic factors are known to influence the human aging process, the proportion of life span and longevity variation explained by them is still controversial. We evaluated the genetic contribution to life span using historical data from three Alpine communities in South Tyrol, Italy. We estimated the heritability of life span and survival to old age (longevity), and we assessed the hypothesis of a common...
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