Article

Therapeutic acetaminophen exposure does not measurably alter human cortical organoid development

2025-10-08

Abstract excerpt

<h4>ABSTRACT</h4> Acetaminophen (APAP) is the most widely used analgesic during pregnancy, yet its effects on prenatal human brain development remain incompletely understood. Epidemiological studies have reported inconsistent associations between prenatal APAP exposure and later neurodevelopmental outcomes, underscoring the need for mechanistic evaluation in human-relevant developmental models. Here, we examined...

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Literature Corpus work: 03451fef-33dd-5090-8037-1105b0431e21
DOI: 10.1101/2025.10.07.681041

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