Defining the filarial N-glycoproteome by glycosite mapping in the human parasitic nematode Brugia malayi

Abstract excerpt

<title>Abstract</title> <p>N-linked glycosylation is a critical post translational modification of eukaryotic proteins. N-linked glycans are present on surface and secreted filarial proteins that play a role in host parasite interactions. Examples of glycosylated <italic>Brugia malayi</italic> proteins have been previously identified but there has not been a systematic study of the N-linked glycoproteome of this...

Topics

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• Disease Models, Animal
• Gene Expression Regulation, Developmental
• Genetic Variation
• Insect symbiosis and bacterial influences
• Parasites and Host Interactions
• Parasitic Diseases Research and Treatment
• Parasitic Infections and Diagnostics
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

0330a62b-9203-5567-b414-616fa8429048

DOI

10.21203/rs.3.rs-2566175/v1