Stage-specific proteomic expression patterns of the human filarial parasite <i>Brugia malayi</i> and its endosymbiont <i>Wolbachia</i>

Abstract excerpt

Global proteomic analyses of pathogens have thus far been limited to unicellular organisms (e.g., protozoa and bacteria). Proteomic analyses of most eukaryotic pathogens (e.g., helminths) have been restricted to specific organs, specific stages, or secretomes. We report here a large-scale proteomic characterization of almost all the major mammalian stages of Brugia malayi, a causative agent of lymphatic...