Immunological genomics of <i>Brugia malayi</i>: filarial genes implicated in immune evasion and protective immunity

Abstract excerpt

Filarial nematodes are metazoan parasites with genome sizes of> 100 million base pairs, probably encoding 15 000-20 000 genes. Within this considerable gene complement, it seems likely that filariae have evolved a spectrum of immune evasion products which underpin their ability to live for many years within the human host. Moreover, no suitable vaccine currently exists for human filarial diseases, and few markers...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Insect symbiosis and bacterial influences
• Share to Parasites and Host Interactions
• Share to Parasitic Diseases Research and Treatment