Article

CircRNA LRIG3 knockdown inhibits the progression of hepatocellular carcinoma by regulating miR-223-3p/MAP2K6 axis and inactivating MAPK/ERK pathway

2020-03-17

Abstract excerpt

<h4>Background: </h4> Emerging evidence suggests that circular RNAs (circRNAs) play critical roles in tumorigenesis. However, the roles and molecular mechanism of circRNA leucine-rich repeat immunoglobulin domain-containing protein 3 (circ_LRIG3) in hepatocellular carcinoma (HCC) have not been investigated. <h4>Methods: </h4>: The expression levels of circ_LRIG3, microRNA-223-3p (miR-223-3p), and mitogen-activated...

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Literature Corpus work: 03175838-6c31-507a-9594-33ca72ea9dcd
DOI: 10.21203/rs.3.rs-17512/v1

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