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Article

Circular RNA EGLN3 silencing represses renal cell carcinoma progression through the miR-1224-3p/HMGXB3 axis

15 Jul 2021

Abstract excerpt

BACKGROUND: Renal cell carcinoma (RCC) is a common tumor of the urinary system, and its global incidence is increasing annually. Circular RNAs (circRNAs) are involved in RCC tumorigenesis; however, the role of circ-EGLN3 (hsa_circ_0031594) derived from the Egl nine homolog 3 (EGLN3) gene in RCC remains undetermined. METHODS: Circ-EGNL3 expression was examined before and after RNase R and actinomycin treatments in...

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PMID: 34274607
DOI: 10.1016/j.acthis.2021.151752

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