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A novel circular RNA circ-LRIG3 facilitates the malignant progression of hepatocellular carcinoma by modulating the EZH2/STAT3 signaling

22 Nov 2020

Abstract excerpt

BACKGROUND: Circular RNA (circRNA) is emerging as an important player in human diseases, especially cancer. In our previous study, we identified a series of deregulated circRNAs in hepatocellular carcinoma (HCC) by performing circRNA microarray expression profile. Here, we aimed to explore the role of circ-LRIG3 (hsa_circ_0027345) in HCC. METHODS: qRT-PCR and western blot were used to asses gene and protein...

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PMID: 33222697
DOI: 10.1186/s13046-020-01779-5

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