Article

Strain-resolved Dynamics of the Lung Microbiome in Patients with Cystic Fibrosis

2020-03-12

Abstract excerpt

<title>Abstract</title> <p>Background In cystic fibrosis, dynamic and complex communities of microbial pathogens and commensals colonize the lung. Cultured isolates from lung sputum reveal high inter- and intraindividual variability in pathogen strains, sequence variants, and phenotypes; disease progression likely depends on the precise combination of infecting strains. Routine clinical protocols, however, provid...

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Literature Corpus work: 02ee1fb8-bd8e-59b5-9a4f-977c9edb0ec4
DOI: 10.21203/rs.3.rs-16882/v1

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