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Clinical Insights from Metagenomic Analysis of Sputum Samples from Patients with Cystic Fibrosis

21 Nov 2013

Abstract excerpt

As DNA sequencing becomes faster and cheaper, genomics-based approaches are being explored for their use in personalized diagnoses and treatments. Here, we provide a proof of principle for disease monitoring using personal metagenomic sequencing and traditional clinical microbiology by focusing on three adults with cystic fibrosis (CF). The CF lung is a dynamic environment that hosts a complex ecosystem composed...

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PMID: 24478471
DOI: 10.1128/jcm.02204-13

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