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Microbiota Present in Cystic Fibrosis Lungs as Revealed by Whole Genome Sequencing

5 Mar 2014

Abstract excerpt

Determination of the precise composition and variation of microbiota in cystic fibrosis lungs is crucial since chronic inflammation due to microorganisms leads to lung damage and ultimately, death. However, this constitutes a major technical challenge. Culturing of microorganisms does not provide a complete representation of a microbiota, even when using culturomics (high-throughput culture). So far, only...

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PMID: 24599149
DOI: 10.1371/journal.pone.0090934

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