Article
Redox Imbalance and Genetic Mutations in Heart Failure: Synergistic Mechanisms and Therapeutic Strategies.
Genes - 11 Feb 2026
Balakrishnan Vinod Kumar, Rajkumar Abinayaa, Ganesh Monisha K G, Kovvuri Harilalith Reddy, Selvam Durgadevi, Krishnamurthy Preetam, Sundaram Sandhya, Periandavan Kalaiselvi, Ramesh Sankaran, Ramamurthy Muralidharan Thoddi, Rajasekaran Namakkal S
Abstract excerpt
Heart failure (HF) is a significant global health challenge, with rising prevalence and a complex, multifactorial pathophysiology. Emerging evidence suggests that disruptions in redox signaling pathways and genetic mutations play critical, synergistic roles in the development and progression of HF. This comprehensive review synthesizes current knowledge on how redox imbalance and genetic alterations interact to...
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