Article
VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis
2024-08-09
Abstract excerpt
<title>Abstract</title> <p>Osteoarthritis (OA), a disease that affects more than 500 million people worldwide, profoundly affects quality of life and the ability to work. The MAPK signaling pathway plays an essential role in various types of inflammatory diseases, including OA. To address the lack of studies focused on synovial cells in OA, we evaluated the expression patterns and roles of the MAPK signaling path...
Topics
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- Bone Metabolism and Diseases
- Cancer-related molecular mechanisms research
- Chemokine receptors and signaling
- Cytokine Signaling Pathways and Interactions
- Inflammatory mediators and NSAID effects
- interferon and immune responses
- Osteoarthritis Treatment and Mechanisms
- Rheumatoid Arthritis Research and Therapies
Identifiers and source
- Literature Corpus work
- 02ca010c-90eb-52bb-a9f3-2688777678d9
- DOI
- 10.21203/rs.3.rs-4646415/v1
