Back to search

Article

Comprehensive Bioinformatics Analysis of Angiogenesis in Knee Osteoarthritis: Identification of Diagnostic Biomarkers and Therapeutic Targets

2025-07-03

Abstract excerpt

<title>Abstract</title> <p>Background Osteoarthritis (OA) is a prevalent disabling disease characterized by cartilage degeneration, subchondral sclerosis, and synovial abnormalities, significantly impairing quality of life. Its pathogenesis involves genetic and immune-inflammatory mechanisms. Angiogenesis and immune infiltration play critical roles in knee osteoarthritis (KOA), though their precise interactions...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b33f793c-a65f-5221-96b4-66380ed37efa
DOI
10.21203/rs.3.rs-7011751/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Comprehensive Bioinformatics Analysis of Angiogenesis in Knee Osteoarthritis: Identification of Diagnostic Biomarkers and Therapeutic TargetsDOI 10.21203/rs.3.rs-7011751/v1
Identification of osteoarthritis-characteristic genes and immunological micro-environment features by bioinformatics and machine learningSemantic proximity
Identification of osteoarthritis-characteristic genes and immunological micro-environment features through bioinformatics and machine learning-based approachesSemantic proximity
Angiogenesis-relevant lncRNA signature for osteosarcoma: prospects for prediction of clinical outcomes and immunotherapeutic efficacySemantic proximity
Biomarker Prediction and Immune Landscape of Angiogenesis in Inflammatory Bowel Disease: Insights from Bioinformatics and Machine Learning ApproachesSemantic proximity
Screening of Potential Biomarkers and Immune Analysis for Osteoarthritis Based on Machine Learning and WGCNASemantic proximity
Integrative analysis and experiments to explore GAS1 as a prognostic target for ovarian cancer based on angiogenesis-related genesSemantic proximity
Comprehensive Analysis of Key Genes, Signaling Pathways and miRNAs in Human Knee Osteoarthritis: Based on BioinformaticsSemantic proximity
Identification of Key Glycolysis-Related Genes in Osteoarthritis and Their Correlation with Immune Infiltration Using Bioinformatics Analysis and Machine LearningSemantic proximity
Identification of immune microenvironment subtypes and clinical risk biomarkers for osteoarthritis based on a machine learning modelSemantic proximity
Integrative Identification of Angiogenesis-Related Genes for Predicting Immune Interaction and Prognosis in LUADSemantic proximity
Implicating Anoikis and CXCR4 in Osteoarthritis: Predictive Modeling and Therapeutic InsightsSemantic proximity
Screening of diagnostic markers related to immune infiltration in osteoarthritis patients based on machine learningSemantic proximity
Select a neighboring publication to make it the new centre.