Emerging roles of microRNA in the intracellular signaling networks of hepatocellular carcinoma.

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs of 19-23 nucleotides that negatively regulate gene expression through binding to the 3'-untranslated regions of target messenger RNAs (mRNAs). Although the miRNA family constitutes only a minor fraction of the human genome, they hold fundamental importance in diverse physiological and developmental processes due to their pleiotropic effects on the post-transcriptional...

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• Apoptosis
• Carcinoma, Hepatocellular
• Cell Cycle
• Genetic Therapy
• Liver Neoplasms