Article
MicroRNAs in hepatocellular carcinoma: regulation, function, and clinical implications.
TheScientificWorldJournal - 1 Jan 2013
Sun Jie, Lu Haiqi, Wang Xian, Jin Hongchuan
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and the third cause of cancer-related death. Poor understanding of the mechanisms underlying the pathogenesis of HCC makes it difficult to be diagnosed and treated at early stage. MicroRNAs (miRNAs), a class of noncoding single-stranded RNAs of ~22 nucleotides in length, posttranscriptionally regulate gene expression by base pairing with...
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